SCHEMBL2287622

SCHEMBL2287622

CCCCCCCCCCC(=O)Oc1ccc[nH]1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.47
POLK Q9UBT6 2/20 0.47
POLL Q9UGP5 2/20 0.47
POLH Q9Y253 2/20 0.47
KMT2A Q03164 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
DGKA P23743 1/20 0.44
MEN1 O00255 2/20 0.44
KDM4E B2RXH2 1/20 0.44
RECQL P46063 1/20 0.44
ALOX15 P16050 1/20 0.43
LMNA P02545 2/20 0.42
HTR1A P08908 1/20 0.42
HTR1B P28222 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2287575 0.98 KMT2A (0.45) POLMPOLKPOLLPOLHKMT2A
SCHEMBL29020316 0.93 KMT2A (0.50) POLMPOLKPOLLPOLHKMT2A
SCHEMBL10396869 0.81 POLM (0.51) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15546549 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15549473 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548862 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548290 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548218 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15549264 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548035 0.76 KMT2A (0.66) POLMPOLKPOLLPOLHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7998726-B2 Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2011-08-16 US claimed
US-7998726-B2 Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2011-08-16 US disclosed
EP-1563304-B1 METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR COMMISSARIAT ENERGIE ATOMIQUE (FR) 2010-09-15 EP disclosed
US-20060035208-A1 Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2006-02-16 US disclosed
EP-1563304-A1 METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR Commissariat A L'Energie Atomique (FR) 2005-08-17 EP disclosed
WO-2004048972-A1 METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2004-06-10 WO disclosed