SCHEMBL22883245

SCHEMBL22883245

c1ccc(-c2ccc(-c3cc(-c4ccccc4)cc(-c4cccc(-c5cccc(-c6ccc7c(c6)C6(c8ccccc8O7)c7ccccc7-c7ccccc76)c5)c4)c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.42
BACE1 P56817 1/20 0.36
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12332626 0.93 PDK2 (0.47) PDK2BACE1
SCHEMBL14278968 0.93 PDK2 (0.47) PDK2BACE1
SCHEMBL25873442 0.93 PDK2 (0.40) PDK2
SCHEMBL15275902 0.92 BACE1 (0.40) PDK2BACE1CA12CA9
SCHEMBL21578466 0.92 PDK2 (0.40) PDK2BACE1
SCHEMBL21677950 0.92 PDK2 (0.38) PDK2BACE1
SCHEMBL24647485 0.91 PDK2 (0.38) PDK2BACE1
SCHEMBL21651571 0.91 PDK2 (0.38) PDK2BACE1
SCHEMBL19298709 0.91 PDK2 (0.38) PDK2BACE1
SCHEMBL20619783 0.91 PDK2 (0.38) PDK2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210013422-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed