⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106858 | 0.77 | — | — | |
| SCHEMBL18534726 | 0.75 | — | — | |
| SCHEMBL14471003 | 0.75 | — | — | |
| SCHEMBL1108355 | 0.75 | — | — | |
| SCHEMBL1106862 | 0.72 | — | — | |
| SCHEMBL22887787 | 0.71 | — | — | |
| SCHEMBL19117377 | 0.71 | — | — | |
| SCHEMBL23976777 | 0.70 | — | — | |
| SCHEMBL18328203 | 0.69 | — | — | |
| SCHEMBL15386621 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760625-A1 | BICYCLIC LACTAMS AS RECEPTOR-INTERACTING PROTEIN-1 (RIP1) KINASE INHIBITORS FOR TREATING E.G. INFLAMMATORY DISEASES | F. Hoffmann-La Roche AG (CH) | 2021-01-06 | — | — | EP | disclosed |