Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 12/20 | 0.52 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288362 | 1.00 | CACNA2D1 (0.52) | CACNA2D1CACNA2D2SLC6A2BTKMEN1 | |
| SCHEMBL2289695 | 0.88 | CACNA2D1 (0.51) | CACNA2D1CACNA2D2SLC6A2MEN1KMT2A | |
| SCHEMBL2289702 | 0.88 | CACNA2D1 (0.51) | CACNA2D1CACNA2D2SLC6A2MEN1KMT2A | |
| SCHEMBL2288797 | 0.87 | CACNA2D1 (0.52) | CACNA2D1CACNA2D2SLC6A2 | |
| SCHEMBL2288791 | 0.87 | CACNA2D1 (0.52) | CACNA2D1CACNA2D2SLC6A2 | |
| SCHEMBL2293095 | 0.87 | CACNA2D1 (0.70) | CACNA2D1CACNA2D2SLC6A2 | |
| SCHEMBL2292019 | 0.86 | CACNA2D1 (0.51) | CACNA2D1CACNA2D2SLC6A2MEN1KMT2A | |
| SCHEMBL2292026 | 0.86 | CACNA2D1 (0.51) | CACNA2D1CACNA2D2SLC6A2MEN1KMT2A | |
| SCHEMBL2289722 | 0.84 | CACNA2D1 (0.48) | CACNA2D1CACNA2D2SLC6A2 | |
| SCHEMBL2289725 | 0.84 | CACNA2D1 (0.48) | CACNA2D1CACNA2D2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998954-B2 | Pyrimidodiazepinone derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |