Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644085 | 1.00 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890335 | 0.89 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890628 | 0.89 | LRRK2 (0.85) | LRRK2 | |
| SCHEMBL29643998 | 0.89 | LRRK2 (0.85) | LRRK2 | |
| SCHEMBL22890489 | 0.88 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29644069 | 0.88 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29644061 | 0.87 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890076 | 0.87 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890355 | 0.87 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890067 | 0.87 | LRRK2 (1.00) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007477-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | E-SCAPE BIO, INC. (US) | 2021-01-14 | — | — | WO | disclosed |