Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626527 | 0.83 | MEN1 (0.35) | NOS3NOS1NOS2MEN1CYP1A2 | |
| SCHEMBL14707849 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707847 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707858 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707855 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707839 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707851 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707834 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL18940384 | 0.81 | FUCA1 (0.52) | FUCA1 | |
| SCHEMBL14707840 | 0.81 | FUCA1 (0.52) | FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953950-B1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | UNIV CALIFORNIA (US) | 2021-01-13 | — | — | EP | disclosed |