SCHEMBL228923

SCHEMBL228923

CN1CN(C)C(=O)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24925402 0.81 CRBN (0.31)
SCHEMBL717518 0.77 BRD4 (0.43)
SCHEMBL12252009 0.77
SCHEMBL22779345 0.72 BRD4 (0.39)
SCHEMBL14428797 0.72 BRD4 (0.52)
SCHEMBL11607389 0.72 KMT2A (0.35)
SCHEMBL17433532 0.72 BRD4 (0.52)
SCHEMBL9881276 0.69
Bromide SCHEMBL11607704 0.69 KMT2A (0.33)
Hydrochloric Acid SCHEMBL11349959 0.69 KMT2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4368621-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND Applied Pharmaceutical Science, Inc. (CN) 2024-05-15 EP claimed
CN-117561259-A Preparation method of nitrogen-containing polycyclic condensed ring compound, intermediate and application thereof 北京志健金瑞生物医药科技有限公司 2024-02-13 CN claimed
EP-2459512-B1 METHOD FOR MANUFACTURING 2,2-DIFLUORETHYLAMIN BAYER IP GMBH (DE) 2016-08-17 EP claimed
CN-102574153-B Thermal ink jet ink composition VIDEOJET TECHNOLOGIES INC 2015-02-18 CN claimed
CN-102076792-B Thermal ink jet ink composition VIDEOJET TECHNOLOGIES INC 2013-12-04 CN claimed
CN-102574153-A Thermal ink jet ink composition VIDEOJET TECHNOLOGIES INC 2012-07-11 CN claimed
US-8188319-B2 Process for preparing 2,2-difluoroethylamine BAYER CROPSCIENCE AG (DE) 2012-05-29 US claimed
US-20110060167-A1 Process for Preparing 2,2-Difluoroethylamine BAYER CROPSCIENCE AG (DE) 2011-03-10 US claimed
CN-1367276-A Method for producing fine fibrous polymer fabric KOREA ADVANCED INST SCI & TECH (KR) 2002-09-04 CN claimed
US-20240158335-A1 A PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLAMINES FROM POLYFLUOROALKYLALCOHOLS University of Strasbourg (FR) 2024-05-16 US disclosed
EP-4368621-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND Applied Pharmaceutical Science, Inc. (CN) 2024-05-15 EP disclosed
CN-115259736-B Halogen-free quaternary amines and their use 亨斯迈石油化学有限责任公司 2024-05-07 CN disclosed
CN-117736228-A Homogeneous organic lithium initiator and preparation method and application thereof 中国石油化工股份有限公司 2024-03-22 CN disclosed
CN-117561259-A Preparation method of nitrogen-containing polycyclic condensed ring compound, intermediate and application thereof 北京志健金瑞生物医药科技有限公司 2024-02-13 CN disclosed
EP-0673388-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY NYCOMED IMAGING AS (NO) 1995-09-27 EP disclosed
CN-1106390-A Azole compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-08-09 CN disclosed
WO-1994029268-A1 IODOPROPARGYL CARBAMATES AND THEIR USE AS BIOCIDES IN THE PROTECTION OF PLANTS AND MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1994-12-22 WO disclosed
EP-0628542-A1 Process for the preparation of organic carbonates BAYER AG (DE) 1994-12-14 EP disclosed
WO-1993024523-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY HAFSLUND NYCOMED AS (NO) 1993-12-09 WO disclosed
CN-86105597-A Make the method for novel pyrazoline compounds 1987-02-25 CN disclosed