SCHEMBL2289330

SCHEMBL2289330

COC=CC(=O)O.[SiH3]O[SiH3]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.44
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40
EGLN3 Q9H6Z9 1/20 0.40
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 5/20 0.32
HSD17B10 Q99714 3/20 0.32
ALOX15 P16050 2/20 0.32
RECQL P46063 1/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023871 0.92
SCHEMBL28910 0.92
SCHEMBL6833025 0.92
SCHEMBL28816672 0.89
Hydrochloric Acid SCHEMBL15352920 0.89
Benzene SCHEMBL9028744 0.86 HCAR2 (0.46) HCAR2TSHRTP53EGLN1EGLN3
Methacrylic Acid SCHEMBL21836019 0.83 HCAR2 (0.39) HCAR2TSHRTP53EGLN1EGLN3
Methacrylic Acid SCHEMBL28015931 0.83 HCAR2 (0.39) HCAR2TSHRTP53EGLN1EGLN3
Propionic Acid SCHEMBL28002953 0.80 FFAR3 (0.48) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL10536996 0.76 TSHR (0.69) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196068-A1 RESIN COMPOSITION FOR OPTICAL LENS AND OPTICAL PACKAGING NAN YA PLASTICS CORPORATION (TW) 2011-08-11 US disclosed