SCHEMBL2289447

SCHEMBL2289447

Oc1ccc(Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.74
ESR2 Q92731 3/20 0.74
MAPT P10636 2/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 1/20 0.47
GAA P10253 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
GFER P55789 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KEAP1 Q14145 1/20 0.46
IDO1 P14902 3/20 0.46
AGXT P21549 2/20 0.46
ABAT P80404 1/20 0.46
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1106684 0.86 IDO1 (0.58) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL2969737 0.86 ESR1 (1.00) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL36454 0.86 ESR1 (1.00) ESR1ESR2MAPTMEN1KMT2A
Diphenylmethane SCHEMBL11376521 0.84 ESR1 (0.52) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL5647781 0.84 ESR1 (0.74) ESR1ESR2MAPTMEN1KMT2A
Parachlorophenol SCHEMBL6119005 0.83 MAPK1 (0.65) ESR1ESR2MAPTMEN1KMT2A
Parachlorophenol SCHEMBL7730292 0.83 MAPK1 (0.65) ESR1ESR2MAPTMEN1KMT2A
Parachlorophenol SCHEMBL28864 0.83
Parachlorophenol SCHEMBL30086664 0.83
SCHEMBL11671660 0.81 MAPT (0.49) ESR1ESR2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509477-B Edge-protection tape 德莎欧洲股份公司 2019-06-21 CN disclosed
CN-103275337-B Cross-linking agent-accelerator system for polyacrylate 德莎欧洲公司 2016-12-28 CN disclosed
CN-102854744-B The manufacture method of photosensitive polymer combination and hardening thing and photoresist 东洋油墨SC控股株式会社 2016-06-29 CN disclosed
CN-103974981-B Hardening resin composition, curable resin formed body, cured resin formed body and their manufacture method and duplexer LINTEC CORP. (JP) 2016-05-18 CN disclosed
CN-101312948-B Biaryl substituted heterocycle inhibitors of lTA4H for treating inflammation DECODE GENETICS EHF 2015-01-14 CN disclosed
CN-103201109-B Gas-barrier film, process for producing same, member for electronic device, and electronic device LINTEC CORP. (JP) 2014-10-22 CN disclosed
CN-104066576-A Gas barrier film, method for producing same, gas barrier film laminate, member for electronic device, and electronic device LINTEC CORP 2014-09-24 CN disclosed
CN-102234211-B Method for preparing diaryl methane with acidic hydrogen SHANGHAI KAITUOZHE CHEMICAL RES MAN CO LTD 2014-09-17 CN disclosed
CN-103974981-A Curable resin composition, curable resin molded body, cured resin molded body, method for producing each of same, and laminate body LINTEC CORP 2014-08-06 CN disclosed
EP-1926708-B1 BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION DECODE GENETICS EHF (IS) 2014-06-18 EP disclosed
EP-0028609-A1 Use of chloronitrophenyl derivatives as selective herbicides and new chloronitrophenyl derivatives. SIEGFRIED AG (CH) 1981-05-20 EP disclosed
US-4251400-A CONTAINING POLYVINYL PYRROLIDONE AS AN ANTICOAGULANT BORDEN, INC. (US) 1981-02-17 US disclosed
WO-1980002493-A1 HERBICIDES SIEGFRIED AG (CH) 1980-11-27 WO disclosed
US-4211551-A 4-/4'-CHLOROBENZYL/PHENOXY ACETIC ACID AND SALTS SIEGFRIED AG (CH) 1980-07-08 US disclosed
US-4182902-A P-(P'-CHLOROBENZYL) PHENOXYACETIC ACID SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed
US-4153803-A Cholesterol-lowering phenoxyalkanoic acid esters SIEGFRIED AKTIENGESELLSCHAFT (CH) 1979-05-08 US disclosed
US-4115393-A Pyridyl alkyl esters of substituted phenoxy alkanoic acids having the ability to reduce the level of fatty substances in the blood SIEGFRIED AKTIENGESELLSCHAFT (CH) 1978-09-19 US disclosed
US-4088474-A Herbicidal agents HOECHST AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed
US-4077962-A WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed