Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | BPTF | Q12830 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | NRAS | P01111 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.42 |
| ▸ | CCNK | O75909 | 7/20 | 0.42 |
| ▸ | CDK9 | P50750 | 7/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.42 |
| ▸ | CDK2 | P24941 | 6/20 | 0.42 |
| ▸ | CDK7 | P50613 | 5/20 | 0.42 |
| ▸ | CCNH | P51946 | 4/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550160 | 1.00 | MAPK1 (0.56) | MAPK1BPTFIKBKBNRASFLT3 | |
| SCHEMBL22895627 | 1.00 | MAPK1 (0.56) | MAPK1BPTFIKBKBNRASFLT3 | |
| Hydrochloric Acid SCHEMBL28551781 | 0.98 | MAPK1 (0.54) | MAPK1BPTFIKBKBNRASFLT3 | |
| Hydrochloric Acid SCHEMBL28551783 | 0.98 | MAPK1 (0.54) | MAPK1BPTFIKBKBNRASFLT3 | |
| SCHEMBL31619957 | 0.89 | MAPK1 (0.64) | MAPK1IKBKBFLT3IRAK1IRAK4 | |
| Trifluoroacetic Acid SCHEMBL28555887 | 0.86 | HRH4 (0.51) | MAPK1BPTFCCNT1CCNKCDK9 | |
| Trifluoroacetic Acid SCHEMBL28555886 | 0.86 | HRH4 (0.51) | MAPK1BPTFCCNT1CCNKCDK9 | |
| SCHEMBL17961847 | 0.83 | CCNT1 (0.41) | MAPK1BPTFCCNT1CCNKCDK9 | |
| SCHEMBL20577266 | 0.83 | SYK (0.44) | MAPK1BPTFCCNKCDK12CDK7 | |
| SCHEMBL17961848 | 0.83 | CCNT1 (0.41) | MAPK1BPTFCCNT1CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358958-B2 | — | — | 2022-06-14 | — | — | US | disclosed |
| US-20210130340-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. | 2021-05-06 | — | — | US | disclosed |
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | KINNATE BIOPHARMA INC. (US) | 2021-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358958-B2 | — | CDK2, CDK1, CDK6 | MAPK1 669/4885BPTF 731/4885IKBKB 191/4885 |
| US-20210130340-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | CDK2, CCNK, CDK1 | MAPK1 412/4885BPTF 780/4885IKBKB 233/4885 |
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | CDK2, CCNK, CDK1 | MAPK1 412/4885BPTF 780/4885IKBKB 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.