Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 8/20 | 0.39 |
| ▸ | BPTF | Q12830 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22895799 | 0.86 | HRH4 (0.39) | HRH4HRH3HRH2SYKKCNH2 | |
| SCHEMBL28544474 | 0.86 | HRH4 (0.39) | HRH4HRH3HRH2SYKKCNH2 | |
| SCHEMBL17961772 | 0.83 | KDM4E (0.46) | HRH4HRH3HRH2RPS6KB1CHEK1 | |
| SCHEMBL17961774 | 0.83 | KDM4E (0.46) | HRH4HRH3HRH2RPS6KB1CHEK1 | |
| Hydrochloric Acid SCHEMBL23295751 | 0.82 | CHEK1 (0.45) | HRH4HRH3HRH2RPS6KB1CHEK1 | |
| SCHEMBL17961789 | 0.82 | CCNT1 (0.42) | HRH4HRH3HRH2SYKKCNH2 | |
| SCHEMBL17961786 | 0.82 | CCNT1 (0.42) | HRH4HRH3HRH2SYKKCNH2 | |
| Hydrochloric Acid SCHEMBL28546461 | 0.82 | CHEK1 (0.45) | HRH4HRH3HRH2RPS6KB1CHEK1 | |
| SCHEMBL23325977 | 0.82 | MKNK1 (0.37) | HRH4HRH3HRH2SYKKCNH2 | |
| Hydrochloric Acid SCHEMBL29777716 | 0.81 | CCNT1 (0.41) | HRH4HRH3HRH2SYKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | KINNATE BIOPHARMA INC. (US) | 2021-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | CDK2, CCNK, CDK1 | HRH4 4367/4885HRH3 3293/4885HRH2 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.