Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 8/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | HTT | P42858 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.80 |
| ▸ | SLC1A3 | P43003 | 7/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761950 | 0.90 | SLC1A3 (0.84) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761945 | 0.90 | SLC1A2 (1.00) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761957 | 0.90 | SLC1A2 (1.00) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761960 | 0.89 | SLC1A2 (0.82) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761993 | 0.88 | SLC1A2 (0.77) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761961 | 0.87 | SLC1A2 (1.00) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761965 | 0.87 | SLC1A2 (1.00) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL18326817 | 0.86 | NPSR1 (0.70) | SLC1A2NPSR1TSHRHTTMEN1 | |
| SCHEMBL29761979 | 0.85 | SLC1A2 (1.00) | SLC1A2NPSR1HTTKMT2ASLC1A3 | |
| SCHEMBL29761966 | 0.84 | SLC1A2 (0.79) | SLC1A2NPSR1TSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011876-A2 | MODULATORS OF EXCITATORY AMINO ACID TRANSPORTERS AND METHODS USING SAME | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2021-01-21 | — | — | WO | disclosed |