Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.54 |
| ▸ | BRD4 | O60885 | 14/20 | 0.42 |
| ▸ | BRD2 | P25440 | 13/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 13/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900401 | 0.91 | BRD4 (0.44) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900734 | 0.88 | BRD4 (0.41) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900680 | 0.88 | BRD4 (0.41) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900456 | 0.88 | QPCT (0.51) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900693 | 0.88 | QPCT (0.52) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900726 | 0.87 | BRD4 (0.40) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900214 | 0.87 | BRD4 (0.40) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900395 | 0.87 | BRD4 (0.40) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900595 | 0.86 | QPCT (0.41) | QPCTBRD4BRD2BRD3CREBBP | |
| SCHEMBL22900187 | 0.86 | QPCT (0.45) | QPCTBRD4BRD2BRD3CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |