Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 19/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900568 | 0.81 | QPCT (0.37) | QPCT | |
| SCHEMBL22900337 | 0.81 | BRD4 (0.45) | QPCTKDM4E | |
| SCHEMBL22900230 | 0.81 | QPCT (0.37) | QPCT | |
| SCHEMBL22900336 | 0.81 | BRD4 (0.38) | QPCT | |
| SCHEMBL22900332 | 0.81 | QPCT (0.37) | QPCT | |
| SCHEMBL22900255 | 0.74 | QPCT (0.54) | QPCTKDM4EALDH1A1HPGD | |
| SCHEMBL24815481 | 0.73 | QPCT (0.40) | QPCT | |
| SCHEMBL24816760 | 0.73 | QPCT (0.40) | QPCT | |
| SCHEMBL24815508 | 0.73 | QPCT (0.40) | QPCT | |
| SCHEMBL24815506 | 0.73 | QPCT (0.40) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |