Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900569 | 0.90 | BRD4 (0.31) | BRD4CREBBPDGAT1 | |
| SCHEMBL22900332 | 0.81 | QPCT (0.37) | BRD4CREBBP | |
| SCHEMBL24816665 | 0.80 | BRD4 (0.34) | BRD4CREBBPDGAT1 | |
| SCHEMBL26833793 | 0.80 | BRD4 (0.34) | BRD4CREBBPDGAT1 | |
| SCHEMBL30166841 | 0.80 | BRD4 (0.34) | BRD4CREBBPDGAT1 | |
| SCHEMBL22900736 | 0.77 | BRD4 (0.38) | BRD4CREBBPMDM2 | |
| SCHEMBL22900529 | 0.76 | BRD4 (0.37) | BRD4CREBBPMDM2DGAT1 | |
| SCHEMBL22900499 | 0.76 | BRD4 (0.39) | BRD4CREBBPMDM2DGAT1 | |
| SCHEMBL22900446 | 0.75 | QPCT (0.37) | BRD4CREBBPMDM2DGAT1 | |
| SCHEMBL22900183 | 0.75 | QPCT (0.37) | BRD4CREBBPMDM2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |