Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900276 | 0.86 | NMT1 (0.41) | NMT1KDM1AKDM1BFPR2PROKR1 | |
| SCHEMBL22900585 | 0.62 | KDM1A (0.36) | KDM1AKDM1B | |
| SCHEMBL28506116 | 0.59 | KDM1A (0.47) | KDM1AKDM1B | |
| SCHEMBL8243578 | 0.58 | KDM1A (0.58) | KDM1AKDM1B | |
| SCHEMBL29739167 | 0.58 | KDM1A (0.58) | KDM1AKDM1B | |
| SCHEMBL13889166 | 0.57 | KDM1A (0.68) | KDM1AKDM1B | |
| SCHEMBL30663472 | 0.57 | BRD4 (0.50) | NMT1FPR2PROKR1BRD4L3MBTL1 | |
| SCHEMBL19519416 | 0.57 | KDM1A (0.52) | KDM1AKDM1B | |
| SCHEMBL27619681 | 0.57 | KDM1A (0.56) | KDM1AKDM1B | |
| SCHEMBL18622406 | 0.56 | NMT1 (0.42) | NMT1FPR2PROKR1L3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |