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Sugi Predict / Compounds / SCHEMBL22900698

SCHEMBL22900698

SCHEMBL22900698

CCCOc1ccc(C2c3c(nn(C)c3C)C(=O)N2c2ccc3nnn(C)c3n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 17/20 0.49
▸ BRD2 P25440 16/20 0.49
▸ BRD3 Q15059 16/20 0.49
▸ CREBBP Q92793 3/20 0.39
▸ QPCT Q16769 2/20 0.39
▸ QPCTL Q9NXS2 1/20 0.39
▸ TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22900766 0.83 QPCT (0.46) BRD4BRD2BRD3CREBBPQPCT
SCHEMBL22900580 0.80 BRD4 (0.49) BRD4BRD2BRD3CREBBPQPCT
SCHEMBL22900583 0.80 BRD2 (0.47) BRD4BRD2BRD3CREBBP
SCHEMBL22900579 0.78 BRD4 (0.53) BRD4BRD2BRD3CREBBP
SCHEMBL22900697 0.76 BRD4 (0.50) BRD4BRD2BRD3CREBBP
SCHEMBL22900582 0.75 BRD4 (0.63) BRD4BRD2BRD3CREBBP
SCHEMBL22900584 0.74 BRD4 (0.73) BRD4BRD2BRD3CREBBPQPCT
SCHEMBL22900604 0.74 QPCT (0.58) BRD4BRD2BRD3CREBBPQPCT
SCHEMBL22900196 0.74 QPCT (0.58) BRD4BRD2BRD3CREBBPQPCT
SCHEMBL22900602 0.74 QPCT (0.58) BRD4BRD2BRD3CREBBPQPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021009068-A1 N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME SCENIC IMMUNOLOGY B.V. (NL) 2021-01-21 — — WO disclosed
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