Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.47 |
| ▸ | BRD2 | P25440 | 5/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 5/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.47 |
| ▸ | QPCT | Q16769 | 15/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22900587 | 0.87 | BRD4 (0.48) | BRD4BRD2BRD3CREBBPQPCT | |
| SCHEMBL22900340 | 0.84 | QPCT (0.49) | BRD4BRD2BRD3CREBBPQPCT | |
| SCHEMBL22900581 | 0.80 | BRD4 (0.48) | BRD4BRD2BRD3CREBBPQPCT | |
| SCHEMBL22900686 | 0.79 | QPCT (0.32) | QPCT | |
| SCHEMBL22900687 | 0.77 | BRD4 (0.41) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22900197 | 0.74 | QPCT (0.56) | BRD4BRD2BRD3CREBBPQPCT | |
| SCHEMBL22900603 | 0.74 | QPCT (0.56) | BRD4BRD2BRD3CREBBPQPCT | |
| SCHEMBL22900605 | 0.74 | QPCT (0.56) | BRD4BRD2BRD3CREBBPQPCT | |
| SCHEMBL22900757 | 0.73 | QPCT (0.39) | QPCTQPCTL | |
| SCHEMBL22900543 | 0.72 | CCR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |