Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.63 |
| ▸ | LYPLA2 | O95372 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276552 | 0.74 | HPGD (0.51) | LYPLA2TRPV1MGLLHPGDMAPK1 | |
| SCHEMBL17276373 | 0.72 | HPGD (0.49) | LYPLA2TRPV1MGLLHPGDMAPK1 | |
| SCHEMBL17276563 | 0.71 | HPGD (0.47) | LYPLA2TRPV1MGLLHPGDMAPK1 | |
| SCHEMBL11199840 | 0.70 | DAGLA (0.42) | DAGLAHPGDMAPK1SMN1; SMN2MEN1 | |
| Oxalic Acid SCHEMBL3600180 | 0.67 | CYP1A2 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6614562 | 0.66 | HPGD (1.00) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11218440 | 0.66 | DAGLA (0.40) | DAGLAHPGDMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL3454812 | 0.65 | HPGD (0.96) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3456729 | 0.65 | HPGD (0.96) | HPGDMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11813984 | 0.64 | HSD17B10 (0.44) | DAGLAHPGDSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120022348-A | Application of PAFAH protein in preparation of products for preventing and/or treating ischemia reperfusion injury | 南开大学 | 2025-05-23 | — | — | CN | disclosed |
| WO-2024077085-A1 | TARGETING PHOSPHOLIPASE A2 (PLA2) IN CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2021011674-A1 | METHODS USEFUL IN TREATING CANCERS HARBORING A KRAS OR HRAS MUTATION OR AMPLIFICATION | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-01-21 | — | — | WO | disclosed |