Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.63 |
| ▸ | LYN | P07948 | 1/20 | 0.63 |
| ▸ | BLK | P51451 | 2/20 | 0.62 |
| ▸ | FGR | P09769 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
| ▸ | CSK | P41240 | 1/20 | 0.62 |
| ▸ | JAK3 | P52333 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 1/20 | 0.62 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.59 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645940 | 0.89 | BTK (0.78) | BTKLCKLYNBLKFGR | |
| SCHEMBL24197239 | 0.87 | BTK (0.66) | BTKLCKLYNBLKFGR | |
| SCHEMBL30416088 | 0.87 | BTK (0.66) | BTKLCKLYNBLKFGR | |
| SCHEMBL25468776 | 0.86 | BTK (0.81) | BTKLCKLYNBLKFGR | |
| SCHEMBL6431891 | 0.86 | BTK (0.66) | BTKLCKLYNBLKFGR | |
| SCHEMBL21338953 | 0.85 | BTK (0.63) | BTKLCKLYNBLKFGR | |
| SCHEMBL21338899 | 0.85 | BTK (0.63) | BTKLCKLYNBLKFGR | |
| SCHEMBL25466396 | 0.84 | BTK (0.67) | BTKLCKLYNBLKFGR | |
| SCHEMBL24197180 | 0.83 | BTK (0.66) | BTKLCKLYNBLKFGR | |
| SCHEMBL30331082 | 0.83 | BTK (0.78) | BTKLCKLYNBLKFGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011428-A1 | HETEROCYCLIC KINASE INHIBITORS | GB005, INC. (US) | 2021-01-21 | — | — | WO | disclosed |