Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.59 |
| ▸ | LCK | P06239 | 4/20 | 0.59 |
| ▸ | LYN | P07948 | 2/20 | 0.59 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.58 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | ITK | Q08881 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | YES1 | P07947 | 1/20 | 0.53 |
| ▸ | HCK | P08631 | 1/20 | 0.53 |
| ▸ | FGR | P09769 | 1/20 | 0.53 |
| ▸ | FER | P16591 | 1/20 | 0.53 |
| ▸ | CSK | P41240 | 1/20 | 0.53 |
| ▸ | TEC | P42680 | 1/20 | 0.53 |
| ▸ | BLK | P51451 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646983 | 0.90 | BTK (0.73) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22902504 | 0.89 | BTK (0.63) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22902667 | 0.87 | TNK2 (0.45) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22902634 | 0.86 | BTK (0.73) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22902505 | 0.86 | BTK (0.73) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL24041322 | 0.85 | BTK (0.78) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22230740 | 0.84 | BTK (0.62) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL29441905 | 0.84 | BTK (0.62) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22243247 | 0.83 | BTK (0.65) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL18269001 | 0.82 | BTK (0.50) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011428-A1 | HETEROCYCLIC KINASE INHIBITORS | GB005, INC. (US) | 2021-01-21 | — | — | WO | disclosed |