Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | TEC | P42680 | 1/20 | 0.51 |
| ▸ | TXK | P42681 | 1/20 | 0.51 |
| ▸ | BMX | P51813 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22902919 | 0.87 | BTK (0.47) | BTKNPC1RAB9A | |
| SCHEMBL22902490 | 0.87 | BTK (0.74) | BTKERBB2TECTXKBMX | |
| SCHEMBL22902915 | 0.86 | BTK (0.45) | BTKERBB2TECTXKBMX | |
| SCHEMBL22902615 | 0.85 | BTK (0.56) | BTKERBB2TECTXKBMX | |
| SCHEMBL22902699 | 0.85 | BTK (0.56) | BTKERBB2TECTXKBMX | |
| SCHEMBL22902916 | 0.85 | BTK (0.58) | BTK | |
| SCHEMBL21903688 | 0.84 | BTK (0.54) | BTKERBB2TECTXKBMX | |
| SCHEMBL21903745 | 0.84 | BTK (0.54) | BTKERBB2TECTXKBMX | |
| SCHEMBL21903683 | 0.84 | BTK (0.54) | BTKERBB2TECTXKBMX | |
| SCHEMBL21965244 | 0.82 | BTK (0.66) | BTKERBB2TECTXKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011428-A1 | HETEROCYCLIC KINASE INHIBITORS | GB005, INC. (US) | 2021-01-21 | — | — | WO | disclosed |