Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22903589 | 1.00 | NR1H2 (0.37) | NR1H2NR1H3KMT2ARORCUSP30 | |
| SCHEMBL22903606 | 0.90 | NR1H2 (0.38) | NR1H2NR1H3KMT2ARORCFPR3 | |
| SCHEMBL22903811 | 0.90 | NR1H2 (0.38) | NR1H2NR1H3KMT2ARORCFPR3 | |
| SCHEMBL26438655 | 0.89 | NR1H2 (0.37) | NR1H2NR1H3KMT2A | |
| SCHEMBL30612496 | 0.89 | NR1H2 (0.37) | NR1H2NR1H3KMT2ARORCUSP30 | |
| SCHEMBL26707623 | 0.88 | KMT2A (0.38) | NR1H2NR1H3KMT2ARORCUSP30 | |
| SCHEMBL26707624 | 0.87 | NR1H2 (0.41) | NR1H2NR1H3KMT2ARORCKCNK3 | |
| SCHEMBL26707622 | 0.85 | NR1H2 (0.40) | NR1H2NR1H3KMT2ARORCFPR3 | |
| SCHEMBL26439338 | 0.84 | KMT2A (0.41) | NR1H2NR1H3KMT2ARORCFPR3 | |
| SCHEMBL26439349 | 0.84 | NR1H2 (0.39) | NR1H2NR1H3KMT2ARORCUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009209-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS | Oncoarendi Therapeutics S.A. (PL) | 2021-01-21 | — | — | WO | disclosed |