SCHEMBL2290618

SCHEMBL2290618

O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12.[SrH2]

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.72
CYP1A2 P05177 3/20 0.53
AURKA O14965 1/20 0.50
AURKB Q96GD4 1/20 0.50
CDK2 P24941 1/20 0.50
COMT P21964 1/20 0.46
APEX1 P27695 1/20 0.45
MEN1 O00255 1/20 0.45
NSD2 O96028 1/20 0.45
POLB P06746 1/20 0.45
IDE P14735 1/20 0.45
DUSP3 P51452 1/20 0.45
CCR6 P51684 1/20 0.45
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45
ATIC P31939 2/20 0.44
ALPL P05186 1/20 0.44
ALPI P09923 1/20 0.44
ALPG P10696 1/20 0.44
DNMT1 P26358 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30233642 0.97 TTR (0.75) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL29363198 0.97 TTR (0.75) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL6242 0.97 TTR (0.75) TTRCYP1A2AURKAAURKBCDK2
Ammonia Solution, Strong SCHEMBL10954121 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Lithium SCHEMBL18420655 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Ammonia Solution, Strong SCHEMBL25312340 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Hydrochloric Acid SCHEMBL7455908 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL460184 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
SCHEMBL8028660 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2
Water SCHEMBL242080 0.95 TTR (0.72) TTRCYP1A2AURKAAURKBCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070244191-A1 Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2007-10-18 US claimed
CN-101054352-A New strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2007-10-17 CN claimed
US-7999009-B2 Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2011-08-16 US disclosed
CN-101054352-B New strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them SERVIER LAB 2011-05-11 CN disclosed
US-20070244191-A1 Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2007-10-18 US disclosed
CN-101054352-A New strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2007-10-17 CN disclosed