⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14087180 | 1.00 | — | — | |
| SCHEMBL13141636 | 1.00 | — | — | |
| SCHEMBL14085997 | 1.00 | — | — | |
| SCHEMBL4204008 | 1.00 | — | — | |
| SCHEMBL24158327 | 0.95 | EPHX1 (1.00) | — | |
| SCHEMBL22452920 | 0.95 | EPHX1 (1.00) | — | |
| SCHEMBL6064188 | 0.95 | EPHX1 (1.00) | — | |
| SCHEMBL17689129 | 0.95 | EPHX1 (1.00) | — | |
| SCHEMBL6063599 | 0.95 | EPHX1 (1.00) | — | |
| SCHEMBL19754812 | 0.95 | EPHX1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |