Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 13/20 | 0.70 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | ITK | Q08881 | 2/20 | 0.60 |
| ▸ | BTK | Q06187 | 4/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | LYN | P07948 | 1/20 | 0.58 |
| ▸ | TEC | P42680 | 1/20 | 0.58 |
| ▸ | TXK | P42681 | 1/20 | 0.58 |
| ▸ | BMX | P51813 | 1/20 | 0.58 |
| ▸ | JAK3 | P52333 | 1/20 | 0.58 |
| ▸ | CD69 | Q07108 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29665636 | 0.91 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL13166285 | 0.91 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL27020093 | 0.91 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL18737417 | 0.88 | SYK (0.67) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL13166664 | 0.86 | SYK (0.67) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL15814664 | 0.86 | SYK (0.66) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL654783 | 0.84 | SYK (0.78) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL14769319 | 0.84 | SYK (0.59) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL656171 | 0.84 | SYK (1.00) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL31294266 | 0.84 | SYK (1.00) | SYKEGFRITKBTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |