Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.69 |
| ▸ | BCL6 | P41182 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 8/20 | 0.53 |
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655628 | 0.88 | AURKA (0.54) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL656928 | 0.85 | AURKA (0.69) | SYKAURKAAURKBCDK2 | |
| SCHEMBL15741405 | 0.85 | AURKA (0.61) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL4119766 | 0.85 | AURKA (0.68) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL655376 | 0.83 | AURKA (0.49) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL19313035 | 0.82 | SYK (0.54) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL656737 | 0.82 | SYK (0.55) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL653572 | 0.82 | AURKA (0.51) | SYKBCL6AURKAJAK2AURKB | |
| SCHEMBL19313055 | 0.81 | SYK (0.72) | SYKBCL6AURKAL3MBTL1 | |
| SCHEMBL15688460 | 0.81 | SYK (0.72) | SYKBCL6AURKAJAK2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617261-A1 | 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wenzhou Medical University (CN) | 2025-09-17 | — | — | EP | disclosed |
| CN-118338898-A | Small molecule inhibitors of oncogenic CHD1L with preclinical anti-colorectal cancer activity | 科罗拉多州立大学董事会（法人团体） | 2024-07-12 | — | — | CN | disclosed |
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |