Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909160 | 0.88 | MAPT (0.36) | MAPTTSHRPOLBALDH1A1GAA | |
| SCHEMBL29729048 | 0.75 | CA1 (0.31) | — | |
| SCHEMBL22909436 | 0.73 | CA1 (0.37) | — | |
| SCHEMBL29671319 | 0.73 | CA1 (0.37) | — | |
| SCHEMBL29671284 | 0.72 | — | — | |
| SCHEMBL22909305 | 0.72 | — | — | |
| SCHEMBL22909278 | 0.71 | HDAC3 (0.31) | POLBALDH1A1 | |
| SCHEMBL29671308 | 0.71 | HDAC3 (0.31) | POLBALDH1A1 | |
| SCHEMBL22909388 | 0.70 | — | — | |
| SCHEMBL22909594 | 0.68 | F2 (0.38) | MAPTTSHRALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |