SCHEMBL22911709

SCHEMBL22911709

CC1(C)CC(S(=O)(=O)COc2c(F)c(F)c(OCc3ccc(F)cc3)c(F)c2F)=NO1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.38
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
MMP13 P45452 2/20 0.33
MAOA P21397 4/20 0.32
HPD P32754 1/20 0.32
CYP19A1 P11511 2/20 0.31
MGMT P16455 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MMP1 P03956 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22911577 0.91 MAOB (0.35) MAOBOPRM1OPRD1CA12CA1
SCHEMBL22911717 0.87 MAOB (0.42) MAOBOPRM1OPRD1CA12MMP13
SCHEMBL22911570 0.87 POLB (0.33) MAOBCA12CA1CA2CA7
SCHEMBL28417941 0.86
SCHEMBL22911716 0.83 MAOB (0.40) MAOBOPRM1OPRD1MMP13HPD
SCHEMBL22911574 0.82
SCHEMBL22911573 0.82
SCHEMBL28410147 0.81
SCHEMBL22911590 0.81 SLC22A12 (0.33)
SCHEMBL22911711 0.81 CA12 (0.30) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021008485-A1 ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE Dongguan HEC Pesticides R&D Co., Ltd. (CN) 2021-01-21 WO disclosed