Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 16/20 | 0.68 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18374548 | 0.81 | DDR1 (1.00) | DDR1DDR2 | |
| SCHEMBL22913194 | 0.77 | DDR1 (0.70) | DDR1NPC1L1 | |
| SCHEMBL20187139 | 0.74 | DDR1 (0.69) | DDR1NPC1L1 | |
| SCHEMBL18374549 | 0.74 | DDR1 (1.00) | DDR1DDR2 | |
| SCHEMBL18374207 | 0.72 | DDR1 (1.00) | DDR1DDR2 | |
| SCHEMBL20187157 | 0.71 | DDR1 (0.64) | DDR1NPC1L1 | |
| SCHEMBL18373989 | 0.70 | DDR1 (1.00) | DDR1DDR2 | |
| SCHEMBL5558533 | 0.70 | DDR1 (0.64) | DDR1NPC1L1 | |
| SCHEMBL22912994 | 0.70 | DDR1 (0.72) | DDR1DDR2NPC1L1 | |
| SCHEMBL22912954 | 0.69 | DDR1 (0.64) | DDR1DDR2NPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3317279-B1 | TRIAZA-SPIRODECANONES AS DDR1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-01-27 | — | — | EP | disclosed |