SCHEMBL22913043

SCHEMBL22913043

Brc1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3OC3C=CC=CC43)n2)c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
NFKB1 P19838 2/20 0.32
MAPK1 P28482 2/20 0.32
NFKB2 Q00653 2/20 0.32
RELA Q04206 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CYP1A2 P05177 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22913845 0.85 SMN1; SMN2 (0.36) TP53MAPTNFKB1MAPK1NFKB2
SCHEMBL23920957 0.83 KDM4E (0.37) TP53MAPTNFKB1MAPK1NFKB2
SCHEMBL23921022 0.82 ENPP1 (0.37) TP53MAPTNFKB1MAPK1NFKB2
SCHEMBL21662067 0.81 ADORA2A (0.33) MAPTL3MBTL1RAB9ATSHRATM
SCHEMBL23921290 0.81 KDM4E (0.40) TP53MAPTNFKB1MAPK1NFKB2
SCHEMBL22923984 0.80 HTT (0.30)
SCHEMBL24949973 0.79 KDM4E (0.31) TP53SMN1; SMN2CYP1A2KDM4EALDH1A1
SCHEMBL23920950 0.79 ENPP1 (0.40) TP53MAPTNFKB1MAPK1NFKB2
SCHEMBL21662066 0.78 CD274 (0.31)
SCHEMBL21304204 0.78 KDM4E (0.36) TP53SMN1; SMN2CYP1A2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015497-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-01-28 WO disclosed