SCHEMBL22913067

SCHEMBL22913067

O=C(CN1CN(c2ccccc2)C2(CCN(C(=O)c3cnc4[nH]ncc4c3)CC2)C1=O)N1CCC(F)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18373971 1.00 DDR1 (1.00) DDR1
SCHEMBL18374190 1.00 DDR1 (1.00) DDR1
SCHEMBL18374141 0.93 DDR1 (1.00) DDR1
SCHEMBL18373982 0.93 DDR1 (1.00) DDR1
SCHEMBL22913070 0.93 DDR1 (1.00) DDR1
SCHEMBL22913325 0.92 DDR1 (0.86) DDR1
SCHEMBL18373884 0.91 DDR1 (1.00) DDR1
SCHEMBL18374154 0.91 DDR1 (1.00) DDR1
SCHEMBL22913695 0.90 DDR1 (1.00) DDR1
SCHEMBL18373885 0.90 DDR1 (1.00) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3317279-B1 TRIAZA-SPIRODECANONES AS DDR1 INHIBITORS HOFFMANN LA ROCHE (CH) 2021-01-27 EP disclosed