SCHEMBL22914213

SCHEMBL22914213

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5ccc6sc7ccc8c(-c9ccccc9)nc9ccccc9c8c7c6c5)cc4)n3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ATM Q13315 1/20 0.43
WHR1 P49842 1/20 0.36
NUDT1 P36639 2/20 0.34
DHODH Q02127 2/20 0.34
LIMK1 P53667 1/20 0.34
PIK3CA P42336 2/20 0.33
ADORA2A P29274 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
PI4KA P42356 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
CYP1A2 P05177 3/20 0.33
CYP3A4 P08684 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2D6 P10635 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22913819 1.00 MEN1 (0.43) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22913785 1.00 MEN1 (0.43) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22913826 0.99 MEN1 (0.44) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22914210 0.99 MEN1 (0.41) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22913825 0.99 MEN1 (0.44) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22913784 0.99 MEN1 (0.44) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22914205 0.96 MEN1 (0.46) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22914194 0.96 MEN1 (0.46) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22913715 0.95 MEN1 (0.41) MEN1KMT2AATMWHR1NUDT1
SCHEMBL22913628 0.93 MEN1 (0.43) MEN1KMT2AATMWHR1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015497-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-01-28 WO disclosed