Geranylgeraniol

Geranylgeraniol

SCHEMBL2291437

CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCO.c1csc(Oc2cccs2)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
MAPT P10636 3/20 0.56
ALOX15 P16050 3/20 0.56
MEN1 O00255 2/20 0.56
CYP3A4 P08684 2/20 0.56
ALDH1A1 P00352 1/20 0.56
UGT1A1 P22309 1/20 0.56
SQLE Q14534 5/20 0.42
TRPV1 Q8NER1 1/20 0.38
PGR P06401 1/20 0.38
HTR1A P08908 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
MAPK1 P28482 1/20 0.38
DRD3 P35462 1/20 0.38
SNCA P37840 1/20 0.38
PDE3A Q14432 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Farnesol SCHEMBL2206101 1.00 KMT2A (0.56) KMT2AMAPTALOX15MEN1CYP3A4
SCHEMBL2291429 0.82 MAPT (0.38) KMT2AMAPTALOX15MEN1CYP3A4
Geranylgeraniol SCHEMBL17557239 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
Geranylgeraniol SCHEMBL127330 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
Geranylgeraniol SCHEMBL156882 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
Geranylgeraniol SCHEMBL23814969 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
SCHEMBL4717874 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
Farnesol SCHEMBL7546574 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
Farnesol SCHEMBL17633996 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4
Solanesol SCHEMBL4762223 0.74 KMT2A (1.00) KMT2AMAPTALOX15MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018116-B1 VITAMIN K2 INTERMEDIATES KAPPA BIOSCIENCE AS (NO) 2020-10-28 EP disclosed
US-10472314-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2019-11-12 US disclosed
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2017-10-05 US disclosed
EP-3018116-A1 VITAMIN K2 INTERMEDIATES Kappa Bioscience As (NO) 2016-05-11 EP disclosed
EP-2346806-B1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2016-01-06 EP disclosed
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2015-07-30 US disclosed
US-9012693-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2015-04-21 US disclosed
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10472314-B2 Process for the preparation of vitamin K2 PROC, VKORC1, VKORC1L1 KMT2A 213/4885MAPT 4698/4885ALOX15 840/4885
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 KMT2A 206/4885MAPT 4724/4885ALOX15 695/4885
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 KMT2A 225/4885MAPT 4700/4885ALOX15 746/4885
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 KMT2A 206/4885MAPT 4724/4885ALOX15 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.