Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 10/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25490410 | 0.94 | GNPAT (0.53) | GNPATFOLH1NOD1NAALAD2RIMKLA | |
| SCHEMBL23189052 | 0.84 | GNPAT (0.44) | GNPATFOLH1NOD1NAALAD2RIMKLA | |
| SCHEMBL19182195 | 0.84 | FOLH1 (0.60) | GNPATFOLH1NOD1NAALAD2RIMKLA | |
| SCHEMBL19182194 | 0.84 | FOLH1 (0.60) | GNPATFOLH1NOD1NAALAD2RIMKLA | |
| SCHEMBL25514715 | 0.83 | PLA2G10 (0.38) | FOLH1 | |
| SCHEMBL30795248 | 0.81 | FOLH1 (0.53) | GNPATFOLH1NOD1NAALAD2RIMKLA | |
| SCHEMBL23189049 | 0.78 | GNPAT (0.50) | GNPATFOLH1NOD1NAALAD2RIMKLA | |
| SCHEMBL26001427 | 0.77 | FOLH1 (0.71) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL16234090 | 0.77 | FOLH1 (0.43) | GNPATFOLH1NOD1 | |
| SCHEMBL23189288 | 0.77 | GNPAT (0.49) | GNPATFOLH1NOD1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098889-A1 | ANTI-HUMAN TROP2 ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND MEDICAL USE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023083381-A1 | BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF | 成都百利多特生物药业有限责任公司 | 2023-05-19 | — | — | WO | disclosed |
| EP-3769786-A1 | ANTIBODY-DRUG CONJUGATE HAVING ACIDIC SELF-STABILIZATION JUNCTION | Sichuan Baili Pharm Co. Ltd (CN) | 2021-01-27 | — | — | EP | disclosed |