Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 10/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | USP2 | O75604 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291722 | 1.00 | CYP1A2 (0.35) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2283182 | 0.88 | ERN1 (0.42) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2288274 | 0.86 | ERN1 (0.39) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2288272 | 0.86 | ERN1 (0.39) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL1667684 | 0.85 | BRD4 (0.37) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL1667681 | 0.85 | BRD4 (0.37) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2146286 | 0.84 | ERN1 (0.36) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2146284 | 0.84 | ERN1 (0.36) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2146930 | 0.84 | ESR2 (0.39) | CYP1A2ALOX15CYP2C19LMNAUSP2 | |
| SCHEMBL2146933 | 0.84 | ESR2 (0.39) | CYP1A2ALOX15CYP2C19LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201555-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-08-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201555-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | ESR1, ESRRA, GPER1 | CYP1A2 1232/4885ALOX15 2595/4885CYP2C19 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.