Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 7/20 | 0.43 |
| ▸ | KIT | P10721 | 4/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 10/20 | 0.41 |
| ▸ | AURKA | O14965 | 4/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | SIK1 | P57059 | 1/20 | 0.37 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.37 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912477 | 0.89 | SRC (0.44) | SRCFLT3KITLCKKDR | |
| SCHEMBL22917461 | 0.89 | SRC (0.44) | SRCFLT3KITLCKKDR | |
| SCHEMBL22917462 | 0.85 | FLT3 (0.46) | SRCFLT3KITLCKKDR | |
| SCHEMBL28912456 | 0.85 | FLT3 (0.46) | SRCFLT3KITLCKKDR | |
| SCHEMBL22917566 | 0.84 | SRC (0.47) | SRCFLT3KITLCKKDR | |
| SCHEMBL29616333 | 0.83 | SRC (0.49) | SRCFLT3KITLCKKDR | |
| SCHEMBL22917463 | 0.83 | SRC (0.49) | SRCFLT3KITLCKKDR | |
| SCHEMBL28912515 | 0.83 | SRC (0.42) | SRCFLT3KITLCKKDR | |
| SCHEMBL22917499 | 0.83 | SRC (0.42) | SRCFLT3KITLCKKDR | |
| SCHEMBL22917588 | 0.83 | CHEK1 (0.43) | SRCFLT3KITLCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016102-A1 | INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2021-01-28 | — | — | WO | disclosed |