Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.86 |
| ▸ | LCK | P06239 | 1/20 | 0.82 |
| ▸ | CSF1R | P07333 | 1/20 | 0.82 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.82 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.82 |
| ▸ | FLT3 | P36888 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919088 | 0.97 | KIT (0.85) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22919086 | 0.93 | KIT (0.94) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22918774 | 0.92 | KIT (1.00) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29615574 | 0.92 | KIT (1.00) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29615492 | 0.92 | KIT (0.86) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22919072 | 0.92 | KIT (0.86) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22918958 | 0.91 | KIT (1.00) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22919069 | 0.91 | KIT (0.85) | KITLCKCSF1RPDGFRBPDGFRA | |
| Idrx-42 SCHEMBL22918830 | 0.90 | KIT (1.00) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22918832 | 0.90 | KIT (0.97) | KITLCKCSF1RPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013864-A1 | 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL) -PYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-01-28 | — | — | WO | disclosed |