SCHEMBL22919871

SCHEMBL22919871

CC(C)(C)OC(=O)Nc1cc(Oc2ccnc3[nH]c(=O)cnc23)ccc1F

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRAF P15056 20/20 0.64
KCNH2 Q12809 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3755100 0.93 BRAF (0.67) BRAFKCNH2
SCHEMBL22919878 0.87 BRAF (0.53) BRAFKCNH2
SCHEMBL28690834 0.86 BRAF (0.68) BRAFKCNH2
SCHEMBL29662245 0.85 BRAF (0.66) BRAFKCNH2
SCHEMBL28684770 0.85 BRAF (0.52) BRAFKCNH2
SCHEMBL3751692 0.85 BRAF (0.66) BRAFKCNH2
SCHEMBL3757667 0.84 BRAF (0.59) BRAFKCNH2
SCHEMBL3052932 0.83 BRAF (0.70) BRAFKCNH2
SCHEMBL30462276 0.82 BRAF (0.51) BRAF
SCHEMBL9909781 0.82 BRAF (0.51) BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021013712-A1 POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES ANAGENESIS BIOTECHNOLOGIES S.A.S. (FR) 2021-01-28 WO disclosed