Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 9/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5437029 | 0.79 | AHR (0.50) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL97761 | 0.79 | CYP2A6 (0.57) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL10923774 | 0.79 | AHR (0.50) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL8051282 | 0.79 | AHR (0.50) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL28168668 | 0.78 | CYP2A6 (0.55) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL9605441 | 0.76 | AHR (0.47) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL10547155 | 0.75 | AHR (0.46) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL29175359 | 0.75 | HPGD (0.61) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL27983052 | 0.75 | HPGD (0.61) | AHRMAPK1PIK3CDTUBB4ATUBB | |
| SCHEMBL10720454 | 0.75 | AHR (0.46) | AHRMAPK1PIK3CDTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |