SCHEMBL22926802

SCHEMBL22926802

C=Cc1c(/C=C\C)c2cc(-c3ccc4c(c3)c3ccccc3n4C)ccc2n1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
ATM Q13315 1/20 0.37
ALDH1A1 P00352 5/20 0.36
MAPT P10636 4/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GPR3 P46089 1/20 0.36
PGR P06401 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
PTGER4 P35408 2/20 0.32
LMNA P02545 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21965264 0.94 KDM4E (0.43) KDM4EL3MBTL1ATMKMT2APTGER4
SCHEMBL22912412 0.90 KDM4E (0.38) KDM4EL3MBTL1ATMPTGER4TSPO
SCHEMBL22912383 0.88 KDM4E (0.38) KDM4EL3MBTL1ATMPTGER4
SCHEMBL22912411 0.88 KDM4E (0.36) KDM4EL3MBTL1ATMPTGER4TSPO
SCHEMBL21249231 0.85 KDM4E (0.32) KDM4EL3MBTL1ATM
SCHEMBL21610874 0.85 KDM4E (0.43) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL19450858 0.83 KDM4E (0.32) KDM4EL3MBTL1ATM
SCHEMBL21139950 0.83 KDM4E (0.37) KDM4EL3MBTL1ATMPTGER4TSPO
SCHEMBL18323681 0.83 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL15382706 0.82 KDM4E (0.40) KDM4EL3MBTL1ATMPTGER4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210028376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 US disclosed