Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455958 | 1.00 | DPP4 (0.45) | DPP4CYP2D6SLC6A4KCNH2LMNA | |
| Hydrochloric Acid SCHEMBL28517808 | 0.99 | CYP3A4 (0.45) | DPP4CYP2D6SLC6A4KCNH2LMNA | |
| SCHEMBL24446082 | 0.85 | CYP2D6 (0.41) | DPP4CYP2D6SLC6A4KCNH2LMNA | |
| SCHEMBL22927151 | 0.85 | CYP2D6 (0.41) | DPP4CYP2D6SLC6A4KCNH2LMNA | |
| SCHEMBL22927230 | 0.82 | CYP2D6 (0.42) | CYP2D6SLC6A4KCNH2LMNAGBA1 | |
| SCHEMBL24446424 | 0.79 | CYP2D6 (0.43) | CYP2D6SLC6A4KCNH2LMNAGBA1 | |
| SCHEMBL22927203 | 0.78 | CYP2D6 (0.47) | CYP2D6SLC6A4KCNH2LMNAGBA1 | |
| SCHEMBL22927209 | 0.76 | CYP2D6 (0.41) | CYP2D6SLC6A4KCNH2LMNAGBA1 | |
| SCHEMBL22927210 | 0.76 | CYP2D6 (0.41) | CYP2D6SLC6A4KCNH2LMNAGBA1 | |
| SCHEMBL24446422 | 0.75 | CYP2D6 (0.42) | CYP2D6SLC6A4KCNH2LMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279774-B | Dibromobenzyl derivative, stereoisomer or salt thereof, preparation method and application | 成都施贝康生物医药科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-112279774-A | Dibromo benzyl derivative, stereoisomer or salt thereof, preparation method and application | 成都施贝康生物医药科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-112279774-B | Dibromobenzyl derivative, stereoisomer or salt thereof, preparation method and application | 成都施贝康生物医药科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| EP-4001260-A1 | DIBROMOBENZYL DERIVATIVE, STEREOISOMER OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Shibeikang Biomedical Technology Co., Ltd. (CN) | 2022-05-25 | — | — | EP | disclosed |
| CN-112279774-A | Dibromo benzyl derivative, stereoisomer or salt thereof, preparation method and application | 成都施贝康生物医药科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| WO-2021012698-A1 | DIBROMOBENZYL DERIVATIVE, STEREOISOMER OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都施贝康生物医药科技有限公司 | 2021-01-28 | — | — | WO | disclosed |