SCHEMBL2292823

SCHEMBL2292823

CCCC(=O)Oc1ccccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
KDM4E B2RXH2 1/20 0.53
RECQL P46063 1/20 0.53
ALOX15 P16050 2/20 0.47
GAA P10253 4/20 0.47
LMNA P02545 2/20 0.47
JAK2 O60674 2/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.46
CA1 P00915 2/20 0.45
CA2 P00918 1/20 0.45
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
BCL9 O00512 1/20 0.42
CTNNB1 P35222 1/20 0.42
POLM Q9NP87 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246062 0.89 MEN1 (0.67) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL688269 0.88 GAA (0.54) KMT2AMEN1KDM4ERECQLGAA
SCHEMBL9312497 0.88 KMT2A (0.59) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL2293567 0.88 MEN1 (0.60) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL5316653 0.87 IAPP (0.50) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL32685038 0.86 MEN1 (0.59) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL32684617 0.86 MEN1 (0.59) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL29834599 0.86 MEN1 (0.59) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL3420357 0.86 MEN1 (0.59) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL9716529 0.86 MEN1 (0.59) KMT2AMEN1KDM4ERECQLALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101380317-B Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD 2010-12-08 CN claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed
CN-1260265-C Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2006-06-21 CN claimed
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP claimed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US claimed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO claimed
CN-1322768-A Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2001-11-21 CN claimed
US-11732223-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc (US) 2023-08-22 US disclosed
CN-114502168-A Oral complement factor D inhibitors 拜奥克里斯特制药公司 2022-05-13 CN disclosed
US-11001789-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc. (US) 2021-05-11 US disclosed
EP-3661901-A1 SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS Eastman Chemical Company (US) 2020-06-10 EP disclosed
WO-2019027948-A1 SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS EASTMAN CHEMICAL COMPANY (US) 2019-02-07 WO disclosed
US-20180037850-A1 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof CRUDE SPILL CLEANING COMPANY, INC. 2018-02-08 US disclosed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO disclosed
CN-1426405-A Novel cyclic amide derivative MITSUBISHI PHARMACEUTICALS INC (JP) 2003-06-25 CN disclosed
US-6521429-B2 Using culture media and yeast extracts CANON KABUSHIKI KAISHA (JP) 2003-02-18 US disclosed
CN-1322768-A Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2001-11-21 CN disclosed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US disclosed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP disclosed
CN-1060782-A MILD SHAMPOO COMPOSITIONS PROCTER & GAMBLE (US) 1992-05-06 CN disclosed