⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765969 | 0.69 | — | — | |
| SCHEMBL1008220 | 0.69 | — | — | |
| SCHEMBL9282368 | 0.67 | — | — | |
| SCHEMBL17423998 | 0.67 | SOS1 (0.33) | — | |
| SCHEMBL19072213 | 0.67 | SOS1 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL17812443 | 0.67 | SOS1 (0.33) | — | |
| SCHEMBL22930557 | 0.67 | SOS1 (0.33) | — | |
| SCHEMBL22442265 | 0.67 | — | — | |
| SCHEMBL9736941 | 0.67 | — | — | |
| SCHEMBL8464116 | 0.67 | SOS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140957-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEONE MEDICINES I GMBH (CH) | 2024-05-02 | — | — | US | disclosed |
| EP-3380101-B1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2021-01-27 | — | — | EP | disclosed |