SCHEMBL22939490

SCHEMBL22939490

c1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)c1cccc3c4c5cccc6c7cc(-n8c9ccccc9c9ccccc98)ccc7n(c65)c4n2c13

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
DUSP3 P51452 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22939488 1.00 KDM4E (0.42) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL22939042 1.00 KDM4E (0.42) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL22939117 0.91 KDM4E (0.42) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL25635029 0.89 KDM4E (0.48) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL25635031 0.89 KDM4E (0.48) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL17146741 0.89 KDM4E (0.48) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL12521348 0.89 KDM4E (0.48) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL25635028 0.89 KDM4E (0.48) KDM4EL3MBTL1ATMMEN1ALDH1A1
SCHEMBL22939674 0.87 KDM4E (0.32) KDM4EL3MBTL1ATM
SCHEMBL25635035 0.86 KDM4E (0.46) KDM4EL3MBTL1ATMMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708355-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-20210032225-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032225-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, BRD1 KDM4E 1758/4885L3MBTL1 571/4885ATM 3797/4885
US-11708355-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, BRD1 KDM4E 1758/4885L3MBTL1 571/4885ATM 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.