Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22939895 | 1.00 | SLC18A3 (0.42) | SLC18A3ABCB1KDM4EALDH1A1KMT2A | |
| SCHEMBL28606331 | 0.96 | SLC18A3 (0.42) | SLC18A3ABCB1KDM4EALDH1A1KMT2A | |
| SCHEMBL29094501 | 0.88 | SMN1; SMN2 (0.37) | SLC18A3ALDH1A1SIGMAR1 | |
| SCHEMBL28151532 | 0.75 | NPC1 (0.45) | ALDH1A1KMT2ACYP11B2 | |
| SCHEMBL8139572 | 0.73 | SLC18A3 (0.39) | SLC18A3ABCB1KDM4EALDH1A1CYP2D6 | |
| SCHEMBL29287218 | 0.73 | SLC18A3 (0.39) | SLC18A3ABCB1KDM4EALDH1A1KMT2A | |
| SCHEMBL19514190 | 0.72 | NPC1 (0.42) | KDM4EALDH1A1KMT2ADRD2DRD4 | |
| Benzene SCHEMBL29077790 | 0.72 | SLC18A3 (0.42) | SLC18A3ABCB1KDM4EALDH1A1DRD2 | |
| SCHEMBL18930217 | 0.70 | SLC18A3 (0.38) | SLC18A3ABCB1KDM4EALDH1A1KMT2A | |
| SCHEMBL22426560 | 0.69 | SLC18A3 (0.36) | SLC18A3KDM4EALDH1A1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584745-B2 | Aromatic heterocyclic compound, intermediate thereof, preparation method therefor, and pharmaceutical composition and use thereof | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2023-02-21 | — | — | US | disclosed |
| US-20210032241-A1 | AROMATIC HETEROCYCLIC COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032241-A1 | AROMATIC HETEROCYCLIC COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | ALK, NOTUM, WEE1 | SLC18A3 2805/4885ABCB1 389/4885KDM4E 913/4885 |
| US-11584745-B2 | Aromatic heterocyclic compound, intermediate thereof, preparation method therefor, and pharmaceutical composition and use thereof | ALK, NOTUM, WEE1 | SLC18A3 2805/4885ABCB1 389/4885KDM4E 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.