Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 8/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944176 | 0.84 | EPHA2 (0.48) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL29578573 | 0.84 | EPHA2 (0.48) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL20241598 | 0.84 | EPHA2 (0.49) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL22943840 | 0.83 | EPHA2 (0.48) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL29578513 | 0.83 | EPHA2 (0.48) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL20241498 | 0.82 | EPHA2 (0.50) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL29827125 | 0.82 | EPHA2 (0.51) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL22943252 | 0.81 | EPHA2 (0.44) | EPHA2EPHB4ERBB2P2RX3P2RX2 | |
| SCHEMBL4510923 | 0.81 | EPHA2 (0.54) | EPHA2EPHB4ERBB2RETNR1H4 | |
| SCHEMBL20242070 | 0.80 | EPHA2 (0.51) | EPHA2EPHB4ERBB2P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728949-A | Heterocyclic compounds as kinase inhibitors and uses thereof | 整体生物科学私人有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-4007757-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | Integral Biosciences Pvt. Ltd. (IN) | 2022-06-08 | — | — | EP | disclosed |
| WO-2021019514-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2021-02-04 | — | — | WO | disclosed |