Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944367 | 1.00 | HDAC6 (0.41) | HDAC6NAMPTKDM4EPOLBNPC1 | |
| SCHEMBL22944368 | 1.00 | HDAC6 (0.41) | HDAC6NAMPTKDM4EPOLBNPC1 | |
| SCHEMBL22944117 | 0.96 | HDAC6 (0.41) | HDAC6KDM4EPOLBALOX15HSD17B10 | |
| SCHEMBL29672374 | 0.96 | HDAC6 (0.41) | HDAC6KDM4EPOLBALOX15HSD17B10 | |
| SCHEMBL29672403 | 0.96 | HDAC6 (0.41) | HDAC6KDM4EPOLBALOX15HSD17B10 | |
| SCHEMBL22944089 | 0.84 | HDAC6 (0.58) | HDAC6 | |
| SCHEMBL22944091 | 0.84 | HDAC6 (0.58) | HDAC6 | |
| SCHEMBL22944092 | 0.81 | HDAC6 (0.59) | HDAC6 | |
| SCHEMBL22944096 | 0.81 | HDAC6 (0.59) | HDAC6 | |
| SCHEMBL29784646 | 0.80 | KDM4E (0.38) | HDAC6KDM4EPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021979-A2 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |