Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CES2 | O00748 | 4/20 | 0.67 |
| ▸ | CES1 | P23141 | 4/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL3296910 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Palmitic Acid SCHEMBL729673 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Octanoic Acid SCHEMBL675368 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Decanoic Acid SCHEMBL11681358 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Undecanoate SCHEMBL8372952 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Nonanoate SCHEMBL8370805 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Arachidic Acid SCHEMBL11685179 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Decanoic Acid SCHEMBL5073590 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Stearic Acid SCHEMBL136593 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Octanoic Acid SCHEMBL28804382 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8226844-B2 | Biocompatible magnetic nanocrystal, powder of a biocompatible magnetic nanocrystal bearing a surface reactive group and preparations thereof | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2012-07-24 | — | — | US | disclosed |
| US-8017031-B2 | Biocompatible magnetic nanocrystal, powder of a biocompatible magnetic nanocrystal bearing a surface reactive group and preparations thereof | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-13 | — | — | US | disclosed |
| US-20110207894-A1 | BIOCOMPATIBLE MAGNETIC NANOCRYSTAL, POWDER OF A BIOCOMPATIBLE MAGNETIC NANOCRYSTAL BEARING A SURFACE REACTIVE GROUP AND PREPARATIONS THEREOF | INSTITUTE OF CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2011-08-25 | — | — | US | disclosed |
| US-20080203351-A1 | paramagnetic or ferromagnetic crystals highly soluble and dispersible in buffers, bonded with a biocompatible macromolecule and an alkyl-containing molecule simultaneously, or a biocompatible macromolecule alone; storage stability | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2008-08-28 | — | — | US | disclosed |