SCHEMBL22951127

SCHEMBL22951127

CSC(=O)CNC(C)(C)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19944904 0.78 PIK3CD (0.43) PIK3CD
SCHEMBL22305053 0.76 PIK3CD (0.42) PIK3CD
SCHEMBL24847195 0.74 PIK3CD (0.41) PIK3CD
SCHEMBL29311481 0.74
SCHEMBL19944905 0.74 PIK3CD (0.41) PIK3CD
SCHEMBL19944903 0.72 TET2 (0.43) PIK3CD
SCHEMBL25101958 0.72 PIK3CD (0.39) PIK3CD
SCHEMBL22952341 0.71 PIK3CD (0.38) PIK3CD
SCHEMBL7965445 0.69
SCHEMBL20953388 0.68 PIK3CD (0.36) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021022163-A2 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2021-02-04 WO disclosed